|
KMID : 1007520140230051709
|
|
Food Science and Biotechnology
2014 Volume.23 No. 5 p.1709 ~ p.1713
|
|
|
In vitro Evaluation of 13 Artemisia Species for an Ability to Release Cholecystokinin
|
|
Kim Kyong
Park Min
Lee Yu-Mi
Rhyu Mee-Ra
Kim Hye-Young
|
|
|
Abstract
|
|
|
|
A total of 13 Artemisia species were evaluated for CCK-releasing activities in STC-1 cells, a model for enteroendocrine cells (EEC). Extracts of Artemisia iwayomogi, A. selengensis, A. rubripes, A. capillaries, and A. keiskeana showed a potent activity for CCK secretion from STC-1 cells. CCK secretion induced by extracts was involved in intracellular Ca2+ increase. Extract-induced CCK secretion involved increases in the intracellular Ca2+ levels, influx of extracellular Ca2+ (at least in part), and activation of TRP and TRPA1 channels. Several Artemisia species are identified for further development of functional foods that can contribute to obesity management.
|
|
|
KEYWORD
|
|
|
Artemisia, cholecystokinin, enteroendocrine cells, obesity
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
 
|